Objective Background: Morphine acts as an analgesic,commonly used to treat cancer pain,but the effective use of morphine......

Clinical usage of opioids in pain relief is dampened by analgesic tolerance after chronic exposure,which is related to o......

Objective Morphine is a potent analgesic.However, its clinical application is restricted due to morphine tolerance.The u......

Morphine is the most effective analgesic for chronic pain including bone cancer pain.So far,studies on morphine toleranc......

Aim: It has been shown that spinal D-amino acid oxidase (DAAO) might be a potential molecular target for the treatment o......

The glial function in morphine tolerance has been explored, but its mechanisms remain unclear.Our previous study has sho......

Clinical usage of opioids in pain relieving was dampened by analgesic tolerance after chronic exposure.The contribution ......

目的探讨电针治疗对骨癌痛吗啡耐受模型大鼠痛行为的影响以及背根神经节降钙素基因相关肽(CGRP)表达的变化。方法40只SD大鼠随机分......

在当今临床治疗中,阿片类药物(如吗啡)已是缓解由创伤、手术以及癌症引起的严重疼痛的首选药物.阿片类药物也越来越多的被应用于慢......

目的 研究N-甲基-M-天冬氨酸受体(NMDA)NR2A亚基在吗啡耐受大鼠脊髓的分布和表达变化.方法 12只雄性SD大鼠随机分成对照组(C组,n=6......